See the changes the CLR team made to the CLR .for NET Framework 3.5 SP1 and the improvements you'll get running your existing CLR 2.0-based apps against this service pack.
MSDN Magazine April 2009
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The CLR security model in the Microsoft .NET Framework 4 has undergone some substantial changes, including the adoption of "Level2" transparency, similar to the Silverlight security model. Mike Rousos provides an in-depth explanation of how that will likely impact authors of AllowPartiallyTrustedCallers (APTCA) libraries.
MSDN Magazine March 2010
Learn about enhanced TimeSpan formatting and parsing features coming in the .NET Framework 4, and some helpful tips for working with TimeSpan values.
MSDN Magazine February 2010
The .NET Framework 4 introduces many updates to the .NET security model that make it much easier to host, secure and provide services to partially trusted code. This article dives into the many features and benefits of the .NET security model.
MSDN Magazine November 2009
Just about everyone who uses Microsoft .NET uses the Base Class Libraries (BCL).When we make the BCL better, almost every managed developer benefits. This column will focus on the new additions to the BCL in .NET 4 beta 1.
Justin Van Patten
MSDN Magazine September 2009
If we learned only one thing about compatibility in the past few years, it is that compatibility is much more than avoiding breaking changes. On the MicrosoftÃÂ®. NET Framework and Visual StudioÃÂ® teams, we do our part to ensure that the products we build are stable platforms that developers can truly rely on.
MSDN Magazine March 2006